Medacta Corporate | Medacta's TiPEEK

RATIONALE

Medacta's TiPEEK cages represent the next generation plasma-sprayed Ti-Coated interbody fusion device. TiPEEK maintains the radiolucency accustomed to with PEEK polymer and provides improved stability. The TiPEEK lumbar posterior and anterior cages, as well as cervical devices, are available in numerous footprints, heights, and sagittal profiles to accommodate various patients.

60’000+ implanted cages with proven clinical results since 2010
Unique Titanium coating with complex micro-roughness
Validated* devices for safe patient use

FUSION RATE
High level fusion rate: ~90% at 3 months post-operatively ^[1]

DISC HEIGHT PRESERVATION
Substantial interbody height restoration and lordosis maintenance^[1]
Low subsidence for significant interverterbral height preservation ^[1]

*according to the FDA guidance, ISO and ASTM standard for tensile, shear, abrasion and compression strength for metallic spray coatings.

Rough, micro-textured TiPEEK surface may lead to:

an improved primary stability due to an increased surface friction
enhanced secondary stability ^[2]
increased migration resistance for short and long term stability ^[2]

TiPEEK cages are compatible with the diagnostic bio-imaging techniques and provide a clear fusion assessment

Unlike solid full Titanium cages or porous Tantalum which create significant artefacts ^[5,6], radiolucent TiPeek technology allows for:

Clear radiographic evaluation; the superficial Ti “halo” may represent an aided marker for cage positioning
CT imaging modality with limited artefacts
MRI scanning with limited interference

Titanium Coated Peek cages (TiPEEK)
incorporate the advantages of both PEEK polymer and Titanium

PEEK HERITAGE

Appropriate spine support
PEEK core provide a native bone interface^[7,8] that may help preventing the subsidence^[10]

Physiological load Sharing
Helps to reduce the stress shielding ^[9]
Allows for proper load force transmission at the implant-tissue interface ^[9]

TITANIUM HERITAGE

Biocompatibility ^[12]

TiPEEK cages are plasma sprayed coated devices
with a unique roughness and a 3D complex topography

ROUGH LAYER
Rough, micro-textured TiPEEK surface may lead to improved primary and secondary stability ^[13,14]

HYDROPHILIC SURFACE
Micro structured Titanium Spray creates hydrophilic surfaces which may improve neovascularization ^[14]

LOW INFLAMMATORY RESPONSE
Ti-coated surfaces reduce potential inflammatory response with reduced chance of fibrous tissue layer around the implant ^[12]

SYNERGY

MYSPINE
Patient Matched Technology

MySpine is a tailor made patient specific guide for spine procedures based on the established MyKnee technology.
The guide is intended to lead the surgeon during the critical steps of accurate pedicle screw placement whilst reducing the surgical time and intra-operative X-ray radiation.

M.U.S.T.
Screw System

The M.U.S.T. Pedicle Screw System is an unconstrained polyaxial screw, rod & connector design applicable to degenerative, deformity and trauma indications using traditional open or MIS surgical approaches

M.U.S.T. MIS Platform

The MUST MIS Platform represents an effective and harmonic concept in terms of minimally invasive solutions. The Mini Open retractor along with the MUST Percutaneous system, can drive the surgeon through an efficient spine surgery result.

PUBLICATIONS

8^thM.O.R.E. International Symposium Proceedings

[1] M.Rickert et al. Transforaminal lumbar interbody fusion in PEEK oblique cages with and without titanium coating: results from a randomized clinical trial

[2] B.Walsh et al. Titanium coated interbody devices

[3] Geert Mahieu et al. A retrospective analysis of patients treated with TiPEEK cages in the cervical and lumbar spine

[4] M. Rauschmann et al, Osteoporotic patients in spine surgery

Supporting Literature

[5] Withmore et al. J Spine Neurosurg 2013, 2:4

[6] Wang JC Spine 1 August 1998 - Volume 23 - Issue 15 - p 1684–1688

[7] Kuhn JL, et al.. Comparison of the trabecular and cortical tissue moduli from human iliac crests. J Orthop Res. 1989;7(6):876-84.

[8] Babyn JD et al. Characterization of a new porous tantalum biomaterial for reconstructive orthopaedics. Proceedings of AAOS, Anaheim, CA. 1999

[9] Sagomonyants KB, Biomaterials 29 (2008) 1563-1572

[10] Chen et al. Comparison of titanium and polyetheretherketone (PEEK) cages in the surgical treatment of multilevel cervical spondylotic myelopathy: a prospective, randomized, control study with over 7-year follow-up. Eur Spine J. 2013 Jul;22(7):1539-46.

[12] Buser D et al. J Biomed Mater Res 1991;25(7):889-902

[13] Olivares-Navarrete et al. Implant materials generate different peri-implant inflammatory factors: poly-ether-ether-ketone promotes fibrosis and microtextured titanium promotes osteogenic factors. Spine (Phila Pa 1976). 2015 Mar 15;40(6):399-404

[14] Olivares-Navarrete et al. Osteoblast maturation and new bone formation in response to titanium implant surface features are reduced with age. J Bone Miner Res. 2012; 27(8); 1773-1783

[15] Pelletier et al. Interbody fusion with peek and a novel compliant titanium fusion device in an aged ovine model. Proceedings of ORS Annual Meeting, 2010, (poster n.1397)